Postdoctoral Fellow - Computational Cancer Biology

City of Hope

Duarte, CA

Job posting number: #7232765 (Ref:10025414)

Posted: March 28, 2024

Salary / Pay Rate: $34.00 - $37.55 / hour

Application Deadline: Open Until Filled

Job Description

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The Nath lab is seeking applicants for a postdoctoral position in computational cancer biology. Our lab aims to enhance cancer treatment outcomes through two main research areas:

  • Investigating the biological mechanisms underlying tumor progression: We use single-cell and bulk multiomic techniques to profile tumor samples, focusing on resistance mechanisms in breast cancer, glioblastomas, colon cancer, and lung cancer.
  • Advancing precision oncology through machine-learning models: We integrate multimodal patient data, including multiomic data and health record information, to develop predictive models for drug response. Furthermore, we work on creating new treatment stratification methods to personalize treatment for individual patients.

More information about the lab can be found here: https://www.nathlab.org

As a successful candidate, you will:

  • Collaborate closely with experimental scientists, mathematicians, and medical oncologists/surgeons to plan, design, and execute computational analyses.
  • Advance the integration of multi-omics and clinical datasets to uncover mechanisms of tumor evolution, therapeutic resistance, and potential biomarkers.
  • Contribute to the development of data analysis pipelines and software tools as a key aspect of this role.
  • Stay updated on the latest advancements in bioinformatics and genomics research and present findings to internal teams and external stakeholders, while also publishing research outcomes and presenting at conferences.
  • Work with the PI to develop a career development plan and participate in various career advancement opportunities.

Your qualifications should include:

  • Ph.D. in bioinformatics, computational biology, or genetics.
  • Applicants with a wet lab background who are highly motivated to receive training in computational biology are also welcomed.
  • Strong fundamentals in cancer biology and basic statistics are essential.
  • Applicants are encouraged to demonstrate proficiency in programming languages like Python/R and omic data analysis.
  • Experience with machine learning algorithms is advantageous.

Additional Information:

  • Applicants are required to submit a CV accompanied by a cover letter outlining how their career objectives align with the research conducted in our lab. Please indicate the expected graduation date if applicable.
  • The candidate's CV should include a detailed list of preprints/publications, along with the names and contact information of three potential referees.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.

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Salary / Pay Rate Information:
Pay Rate: $34.00 - $37.55 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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