Research Technician III - Neuroscience
Baylor College of Medicine
Houston, TX
Job posting number: #7199772 (Ref:17895-en_US)
Posted: December 8, 2023
Job Description
Summary
Dr. Jiang’s laboratory focuses on three related questions regarding brain circuits:
- How many cell types are there in each brain region and how they connect each other to form a normal, functional circuit
- What are unique cell types and organization principles that may have been evolved to endow the primate brain with superb computational capabilities for the complex cognitive processes characteristic of primates
- How stereotypical wiring principles among cell types are impacted by distinct neuropsychiatric conditions.
To this end, we developed and employ a multi-disciplinary approach that includes multi-cell patch recording (up to 12 simultaneous recordings), morphological recovery, single-cell RNA sequencing, optogenetic techniques, and machine learning. Using this integrated approach, we perform large-scale, multidisciplinary profiling of individual neurons in a brain circuit, including their electrophysiological properties, morphology, transcriptome, and connections, to decipher the comprehensive circuit blueprint in different brain regions across species. We also use sophisticated mouse genetic models, in vivo whole-cell recordings, two-photon calcium imaging, and behavioral assays to dissect the functional roles of each cell type in the information processing.
To know more about the lab, please click on the link below.
https://www.bcm.edu/research/labs/xiaolong-jiang
Job Duties
- Maintains mouse colonies, genotyping, PCR.
- Prepares for single-cell RNA-sequencing.
- Performs basic immunostaining and other histological staining.
- Performs neuronal reconstruction with Neurolucida.
- Collects, compiles, and analyzes data.
- Documents results of experiments.
- Assists PI and postdocs in related projects.
Minimum Qualifications
- Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
- One year of relevant experience.
Preferred Qualifications
- Master's degree in basic science or a related field.
- Prefer to have directly related experience for more than one year.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
17895
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Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
